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Cell-Specific Metabolism and Pathogenesis of Transmembrane Prion Protein
The C-transmembrane form of prion protein ((Ctm)PrP) has been implicated in prion disease pathogenesis, but the factors underlying its biogenesis and cyotoxic potential remain unclear. Here we show that (Ctm)PrP interferes with cytokinesis in cell lines where it is transported to the plasma membrane...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1430324/ https://ncbi.nlm.nih.gov/pubmed/16537913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.7.2697-2715.2006 |
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