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SUMO Modification of Human XRCC4 Regulates Its Localization and Function in DNA Double-Strand Break Repair

The nonhomologous end-joining (NHEJ) pathway is responsible for rejoining the majority of double-strand breaks in mammalian cells, including the programmed breaks introduced by V(D)J recombination. The regulation of the enzymatic activities associated with this recombination pathway is still largely...

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Autors principals: Yurchenko, Vyacheslav, Xue, Zhu, Sadofsky, Moshe J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430232/
https://ncbi.nlm.nih.gov/pubmed/16478998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.5.1786-1794.2006
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