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Kinetics and metabolism of pyrazolones (propyphenazone, aminopyrine and dipyrone)

1 Propyphenazone 220 mg was administered orally to volunteers. Maximum plasma concentrations between 1.5 μg/ml and 3.5 μg/ml were found 30 min later. After comparable doses plasma concentrations in dog and rabbit were lower. The distribution volumes were 2 1/kg. 2 The major metabolic route of propyp...

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Detalhes bibliográficos
Main Authors: Volz, Manfred, Kellner, Hans-Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430198/
https://ncbi.nlm.nih.gov/pubmed/7002187
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