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Nephrotoxicity of mild analgesics in the Gunn strain of rat

1 Homozygous members of the Gunn strain of rat, mutant Wistars jaundiced from lack of the enzyme uridine diphosphate glucuronyl transferase, are highly susceptible to analgesic-induced renal papillary necrosis. 2 A single oral dose of aspirin, phenacetin or paracetamol will produce the lesion, a cir...

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Bibliografiske detaljer
Hovedforfatter: Axelsen, Roy A.
Format: Artigo
Sprog:Inglês
Udgivet: 1980
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430177/
https://ncbi.nlm.nih.gov/pubmed/6776978
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