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Nephrotoxicity of mild analgesics in the Gunn strain of rat
1 Homozygous members of the Gunn strain of rat, mutant Wistars jaundiced from lack of the enzyme uridine diphosphate glucuronyl transferase, are highly susceptible to analgesic-induced renal papillary necrosis. 2 A single oral dose of aspirin, phenacetin or paracetamol will produce the lesion, a cir...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1980
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1430177/ https://ncbi.nlm.nih.gov/pubmed/6776978 |
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