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Plasma protein binding of valproic acid in healthy subjects and in patients with renal disease.

1 Based on the Scatchard plot of the binding data of valproic acid (VPA) it is concluded that the drug is bound by two groups of binding sites with the association constants K1=40.0 X 10(-3) and K2=0.39 X 10(3), and the number of binding sites n1=1.5 and n2=6.8. 2 The binding is dependent on dialysi...

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Bibliografski detalji
Glavni autori: Gugler, R, Mueller, G
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1429355/
https://ncbi.nlm.nih.gov/pubmed/350249
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