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Plasma protein binding of valproic acid in healthy subjects and in patients with renal disease.

1 Based on the Scatchard plot of the binding data of valproic acid (VPA) it is concluded that the drug is bound by two groups of binding sites with the association constants K1=40.0 X 10(-3) and K2=0.39 X 10(3), and the number of binding sites n1=1.5 and n2=6.8. 2 The binding is dependent on dialysi...

詳細記述

保存先:
書誌詳細
主要な著者: Gugler, R, Mueller, G
フォーマット: Artigo
言語:Inglês
出版事項: 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1429355/
https://ncbi.nlm.nih.gov/pubmed/350249
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