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Comparative effects of aspirin and diflunisal on prostaglandin synthetase from human platelets and sheep seminal vesicles

1 We have compared the effects of diflunisal on prostaglandin (PG) synthetase from human platelets and sheep seminal vesicles (SSV) by measuring malonaldehyde, PG products, and rabbit aorta contraction. 2 Aspirin inhibits PG synthetase by covalently acetylating the enzyme. Inhibition is dependent on...

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Detalhes bibliográficos
Main Authors: Majerus, Philip W., Stanford, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428838/
https://ncbi.nlm.nih.gov/pubmed/406909
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