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Isolation of human Dna2 endonuclease and characterization of its enzymatic properties

In eukaryotes, the creation of ligatable nicks in DNA from flap structures generated by DNA polymerase δ-catalyzed displacement DNA synthesis during Okazaki fragment processing depends on the combined action of Fen1 and Dna2. These two enzymes contain partially overlapping but distinct endonuclease...

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Bibliografiske detaljer
Main Authors: Kim, Jeong-Hoon, Kim, Hee-Dai, Ryu, Gi-Hyuck, Kim, Do-Hyung, Hurwitz, Jerard, Seo, Yeon-Soo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428795/
https://ncbi.nlm.nih.gov/pubmed/16595799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl102
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