Childhood leukaemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia.

6-Mercaptopurine is extensively used in the treatment of childhood lymphoblastic leukaemia to prolong the duration of remission achieved with other drugs. The response to remission maintenance therapy varies widely. We investigated the relationship between red blood cell 6-thioguanine nucleotide, a...

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Bibliographic Details
Main Authors: Lennard, L, Rees, C A, Lilleyman, J S, Maddocks, J L
Format: Artigo
Language:Inglês
Published: 1983
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428034/
https://ncbi.nlm.nih.gov/pubmed/6578834
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