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Effect of urine pH on the elimination of phenoperidine.

The effect of urine pH on the plasma concentration and elimination of phenoperidine and its main metabolites was studied in six volunteers. The clearance of unchanged phenoperidine in acid urine was significantly greater than in neutral or alkaline urine. By contrast, the elimination of its basic me...

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Bibliographic Details
Main Authors: Milne, L A, Williams, N E, Calvey, T N, Murray, G R, Chan, K
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427958/
https://ncbi.nlm.nih.gov/pubmed/6882616
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