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Effect of urine pH on the elimination of phenoperidine.

The effect of urine pH on the plasma concentration and elimination of phenoperidine and its main metabolites was studied in six volunteers. The clearance of unchanged phenoperidine in acid urine was significantly greater than in neutral or alkaline urine. By contrast, the elimination of its basic me...

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Detalhes bibliográficos
Main Authors: Milne, L A, Williams, N E, Calvey, T N, Murray, G R, Chan, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427958/
https://ncbi.nlm.nih.gov/pubmed/6882616
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