In Vivo Efficacy of Aerosolized Nanostructured Itraconazole Formulations for Prevention of Invasive Pulmonary Aspergillosis

Aerosolized evaporative precipitation into aqueous solution and spray freezing into liquid nanostructured formulations of itraconazole as prophylaxis significantly improved survival relative to commercial itraconazole oral solution and the control in a murine model of invasive pulmonary aspergillosi...

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Main Authors: Hoeben, Barbara J., Burgess, David S., McConville, Jason T., Najvar, Laura K., Talbert, Robert L., Peters, Jay I., Wiederhold, Nathan P., Frei, Bradi L., Graybill, John R., Bocanegra, Rosie, Overhoff, Kirk A., Sinswat, Prapasri, Johnston, Keith P., Williams, Robert O.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
主題:
Experimental Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426984/
https://ncbi.nlm.nih.gov/pubmed/16569882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1552-1554.2006
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