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In Vivo Efficacy of Aerosolized Nanostructured Itraconazole Formulations for Prevention of Invasive Pulmonary Aspergillosis

Aerosolized evaporative precipitation into aqueous solution and spray freezing into liquid nanostructured formulations of itraconazole as prophylaxis significantly improved survival relative to commercial itraconazole oral solution and the control in a murine model of invasive pulmonary aspergillosi...

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Detalhes bibliográficos
Main Authors: Hoeben, Barbara J., Burgess, David S., McConville, Jason T., Najvar, Laura K., Talbert, Robert L., Peters, Jay I., Wiederhold, Nathan P., Frei, Bradi L., Graybill, John R., Bocanegra, Rosie, Overhoff, Kirk A., Sinswat, Prapasri, Johnston, Keith P., Williams, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426984/
https://ncbi.nlm.nih.gov/pubmed/16569882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1552-1554.2006
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