In Vivo Efficacy of Aerosolized Nanostructured Itraconazole Formulations for Prevention of Invasive Pulmonary Aspergillosis

Aerosolized evaporative precipitation into aqueous solution and spray freezing into liquid nanostructured formulations of itraconazole as prophylaxis significantly improved survival relative to commercial itraconazole oral solution and the control in a murine model of invasive pulmonary aspergillosi...

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Hlavní autoři: Hoeben, Barbara J., Burgess, David S., McConville, Jason T., Najvar, Laura K., Talbert, Robert L., Peters, Jay I., Wiederhold, Nathan P., Frei, Bradi L., Graybill, John R., Bocanegra, Rosie, Overhoff, Kirk A., Sinswat, Prapasri, Johnston, Keith P., Williams, Robert O.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426984/
https://ncbi.nlm.nih.gov/pubmed/16569882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1552-1554.2006
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