Maribavir Pharmacokinetics and the Effects of Multiple-Dose Maribavir on Cytochrome P450 (CYP) 1A2, CYP 2C9, CYP 2C19, CYP 2D6, CYP 3A, N-Acetyltransferase-2, and Xanthine Oxidase Activities in Healthy Adults

Maribavir (1263W94, VP-41263) is an oral anticytomegalovirus agent under clinical development. The pharmacokinetics and safety of maribavir and the effects of maribavir on the activities of cytochrome P450 (CYP) 1A2, CYP 2C9, CYP 2C19, CYP 2D6, CYP 3A, N-acetyltransferase-2 (NAT-2), and xanthine oxi...

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Bibliografiset tiedot
Päätekijät: Ma, Joseph D., Nafziger, Anne N., Villano, Stephen A., Gaedigk, Andrea, Bertino, Joseph S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2006
Aiheet:
Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426970/
https://ncbi.nlm.nih.gov/pubmed/16569820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1130-1135.2006
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