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Ritonavir Increases Plasma Amprenavir (APV) Exposure to a Similar Extent when Coadministered with either Fosamprenavir or APV

To compare the effect of ritonavir on plasma amprenavir pharmacokinetics, healthy adults received either fosamprenavir (700 mg twice a day [BID]) or amprenavir (600 mg BID) alone and in combination with ritonavir (100 mg BID). Ritonavir increased plasma amprenavir pharmacokinetic parameters to a sim...

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Autori principali: Wire, Mary B., Baker, Katherine L., Jones, Lori S., Shelton, Mark J., Lou, Yu, Thomas, Greg J., Berrey, M. Michelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426966/
https://ncbi.nlm.nih.gov/pubmed/16569890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1578-1580.2006
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