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Gentamicin Causes Apoptosis at Low Concentrations in Renal LLC-PK(1) Cells Subjected to Electroporation
Gentamicin accumulates in the lysosomes of kidney proximal tubular cells and causes apoptosis at clinically relevant doses. Gentamicin-induced apoptosis can be reproduced with cultured renal cells, but only at high extracellular concentrations (1 to 3 mM; 0.4 to 1.2 g/liter) because of its low level...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1426926/ https://ncbi.nlm.nih.gov/pubmed/16569831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1213-1221.2006 |
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