The CiaRH System of Streptococcus pneumoniae Prevents Lysis during Stress Induced by Treatment with Cell Wall Inhibitors and by Mutations in pbp2x Involved in β-Lactam Resistance

The two-component signal-transducing system CiaRH of Streptococcus pneumoniae plays an important role during the development of beta-lactam resistance in laboratory mutants. We show here that a functional CiaRH system is required for survival under many different lysis-inducing conditions. Mutants w...

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Bibliographic Details
Main Authors: Mascher, Thorsten, Heintz, Manuel, Zähner, Dorothea, Merai, Michelle, Hakenbeck, Regine
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Molecular Biology of Pathogens
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426552/
https://ncbi.nlm.nih.gov/pubmed/16484208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.5.1959-1968.2006
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