New Aspects of the Interplay between Penicillin Binding Proteins, murM, and the Two-Component System CiaRH of Penicillin-Resistant Streptococcus pneumoniae Serotype 19A Isolates from Hungary

The Streptococcus pneumoniae clone Hungary(19A)-6 expresses unusually high levels of β-lactam resistance, which is in part due to mutations in the MurM gene, encoding a transferase involved in the synthesis of branched peptidoglycan. Moreover, it contains the allele ciaH232, encoding the histidine k...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Schweizer, Inga, Blättner, Sebastian, Maurer, Patrick, Peters, Katharina, Vollmer, Daniela, Vollmer, Waldemar, Hakenbeck, Regine, Denapaite, Dalia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487634/
https://ncbi.nlm.nih.gov/pubmed/28483958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00414-17
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