Molecular Characterization of Isoniazid Resistance in Mycobacterium tuberculosis: Identification of a Novel Mutation in inhA

Multiplex allele-specific PCRs detecting katG codon 315 and mabA (bp −15) mutations could specifically identify 77.5% of isoniazid-resistant Mycobacterium tuberculosis strains in the South China region. One clinical isolate harboring InhA Ile194Thr was characterized to show strong association with i...

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Detalhes bibliográficos
Main Authors: Leung, E. T. Y., Ho, P. L., Yuen, K. Y., Woo, W. L., Lam, T. H., Kao, R. Y., Seto, W. H., Yam, W. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426451/
https://ncbi.nlm.nih.gov/pubmed/16495272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.1075-1078.2006
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