VP35 Knockdown Inhibits Ebola Virus Amplification and Protects against Lethal Infection in Mice

Phosphorodiamidate morpholino oligomers (PMO) are a class of uncharged single-stranded DNA analogs modified such that each subunit includes a phosphorodiamidate linkage and morpholine ring. PMO antisense agents have been reported to effectively interfere with the replication of several positive-stra...

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Hlavní autoři: Enterlein, Sven, Warfield, Kelly L., Swenson, Dana L., Stein, David A., Smith, Jeffery L., Gamble, C. Scott, Kroeker, Andrew D., Iversen, Patrick L., Bavari, Sina, Mühlberger, Elke
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426423/
https://ncbi.nlm.nih.gov/pubmed/16495261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.984-993.2006
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