Metallothionein isoform 2A expression is inducible and protects against ROS-mediated cell death in rotenone-treated HeLa cells

The role of MT (metallothionein) gene expression was investigated in rotenone-treated HeLa cells to induce a deficiency of NADH:ubiquinone oxidoreductase (complex I). Complex I deficiency leads to a diversity of cellular consequences, including production of ROS (reactive oxygen species) and apoptos...

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Detalhes bibliográficos
Main Authors: Reinecke, Fimmie, Levanets, Oksana, Olivier, Yolanda, Louw, Roan, Semete, Boitumelo, Grobler, Anne, Hidalgo, Juan, Smeitink, Jan, Olckers, Antonel, Van Der Westhuizen, Francois H.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422768/
https://ncbi.nlm.nih.gov/pubmed/16402917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051253
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