Sulfonylurea Receptor Knockout Causes Glucose Intolerance in Mice That is Not Alleviated by Concomitant Somatostatin Subtype Receptor 5 Knockout

OBJECTIVE: To examine the long-term effects of Sur KO, SSTR5 KO, and double Sur/SSTR5 KO on insulin secretion and glucose regulation. SUMMARY BACKGROUND DATA: The sulfonylurea receptor (Sur) and somatostatin receptor type 5 (SSTR5) play an integral role in the regulatory pathways of the endocrine pa...

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Bibliographic Details
Main Authors: Norman, Michael, Moldovan, Stefan, Seghers, Victor, Wang, Xiao-Ping, DeMayo, Francesco J., Brunicardi, F. Charles
Format: Artigo
Language:Inglês
Published: 2002
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Scientific Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422505/
https://ncbi.nlm.nih.gov/pubmed/12035032
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