Selective inhibition of immature CD4-CD8+ thymocyte proliferation, but not differentiation, by the thymus atrophy-inducing compound di-n-butyltin dichloride.

Effects of the thymus atrophy-inducing organotin compound di-n-butyltin dichloride (DBTC) on the differentiation and proliferation of immature rat thymocyte subsets were studied in vivo and in vitro. Incubation of freshly isolated CD4-CD8- or immature CD4-CD8+ (characterized as CD4-CD53-) thymocytes...

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Main Authors: Pieters, R H, Bol, M, Ariëns, T, Punt, P, Seinen, W, Bloksma, N, Penninks, A H
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422326/
https://ncbi.nlm.nih.gov/pubmed/8157274
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