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Nedocromil sodium acts directly on human B cells to inhibit immunoglobulin production without affecting cell growth.

The effect of nedocromil sodium (NES) on human immunoglobulin (Ig) isotypes, IgG subclasses and IgA subclasses was studied. NES inhibited IgM and IgA1 production from human lymphoblastoid B-cell lines CBL and GM-1056, respectively, in a dose-dependent fashion. This inhibition was not due to decrease...

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Detalhes bibliográficos
Main Authors: Kimata, H, Fujimoto, M, Mikawa, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422294/
https://ncbi.nlm.nih.gov/pubmed/8132219
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