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Nedocromil sodium acts directly on human B cells to inhibit immunoglobulin production without affecting cell growth.

The effect of nedocromil sodium (NES) on human immunoglobulin (Ig) isotypes, IgG subclasses and IgA subclasses was studied. NES inhibited IgM and IgA1 production from human lymphoblastoid B-cell lines CBL and GM-1056, respectively, in a dose-dependent fashion. This inhibition was not due to decrease...

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Bibliografiske detaljer
Main Authors: Kimata, H, Fujimoto, M, Mikawa, H
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422294/
https://ncbi.nlm.nih.gov/pubmed/8132219
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