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Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors.

Pretreatment of mice with capsaicin resulted in approximately 40% inhibition of the polymorphonuclear leucocyte (PMN) influx elicited by interleukin-1 (IL-1) injected into a murine air-pouch. This inhibition was mimicked by two selective antagonists of neurokinin-1 (NK-1) tachykinin (TK) receptors,...

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Main Authors: Perretti, M, Ahluwalia, A, Flower, R J, Manzini, S
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422103/
https://ncbi.nlm.nih.gov/pubmed/7503947
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