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Dissociation of interleukin-2 production from the cell activation in response to the mitogenic lectin in peripheral CD4+ T cells of LEC mutant rats.

A mutant strain of rat, LEC, exhibits a novel maturational arrest of T cells in the thymus, that is, an arrest of the differentiation from CD4+ CD8+ to CD4+ CD8- cells. However, CD4+ T cells were found to arise in lymph nodes (LN) of LEC rats. These CD4+ T cells were T-cell receptor (TcR)/CD3+ and t...

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Bibliografische gegevens
Hoofdauteurs: Sakai, T, Agui, T, Muramatsu, Y, Yamada, T, Matsumoto, K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421972/
https://ncbi.nlm.nih.gov/pubmed/8104885
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