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Xanthine derivatives: comparison between suppression of tumour necrosis factor-alpha production and inhibition of cAMP phosphodiesterase activity.

Several in vitro and in vivo studies have demonstrated suppression of tumour necrosis factor-alpha (TNF-alpha) synthesis by pentoxifylline. In the present study we compared the effect of pentoxifylline with that of five other xanthine derivatives. We addressed two questions. First, what is the relat...

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Bibliografiske detaljer
Main Authors: Semmler, J, Gebert, U, Eisenhut, T, Moeller, J, Schönharting, M M, Alléra, A, Endres, S
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421886/
https://ncbi.nlm.nih.gov/pubmed/8388363
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