Major histocompatibility complex class II-restricted cytotoxicity by self-myelin basic protein-reactive T-cell hybridomas: evidence for a tumour necrosis factor-independent nucleolytic mechanism.

Direct cytotoxicity by class II-restricted T cells has been proposed as a potential mechanism in autoimmune tissue damage, as well as in immunoregulation. We used I-A(s)-restricted non-granular cytotoxic T-cell hybridomas (BP24.29 and BP47.7), specific for self-determinants on myelin basic protein (...

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Autores principales: Rayner, D C, Petrycky-Cox, L D, Diocee, M, Rector, E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421799/
https://ncbi.nlm.nih.gov/pubmed/7682537
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