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Major histocompatibility complex class II-restricted cytotoxicity by self-myelin basic protein-reactive T-cell hybridomas: evidence for a tumour necrosis factor-independent nucleolytic mechanism.
Direct cytotoxicity by class II-restricted T cells has been proposed as a potential mechanism in autoimmune tissue damage, as well as in immunoregulation. We used I-A(s)-restricted non-granular cytotoxic T-cell hybridomas (BP24.29 and BP47.7), specific for self-determinants on myelin basic protein (...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1421799/ https://ncbi.nlm.nih.gov/pubmed/7682537 |
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