Differential effects of a murine and chimeric mouse/human anti-interleukin-2 receptor antibody on human T-cell proliferation.

The preference for interleukin-2 receptor (IL-2R) expression on activated, compared with resting T lymphocytes makes the IL-2R a promising target for selective immunosuppressive therapy. To increase the potential therapeutic effectiveness of anti-IL-2R monoclonals, a chimeric mouse/human variant was...

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Bibliographic Details
Main Authors: Rose, B, Gillespie, A, Wunderlich, D, Kelley, K, Dzuiba, J, Shedd, D, Cahill, K, Zerler, B
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421677/
https://ncbi.nlm.nih.gov/pubmed/1526654
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