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HUMAN BUT NOT YEAST CHD1 BINDS DIRECTLY AND SELECTIVELY TO HISTONE H3 METHYLATED AT LYSINE 4 VIA ITS TANDEM CHROMODOMAINS

Defining the protein factors that directly recognize post-translational, covalent histone modifications is essential towards understanding the impact of these chromatin ‘marks’ on gene regulation. In the current study, we identify human CHD1, an ATP-dependent chromatin remodeling protein, as a facto...

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Библиографические подробности
Главные авторы: Sims, Robert J., Chen, Chi-Fu, Santos-Rosa, Helena, Kouzarides, Tony, Patel, Smita S., Reinberg*, Danny
Формат: Artigo
Язык:Inglês
Опубликовано: 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421377/
https://ncbi.nlm.nih.gov/pubmed/16263726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C500395200
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