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Harnessing preclinical mouse models to inform human clinical cancer trials
The urgent need for better cancer treatments has stimulated interest in employing small-animal models to evaluate potential drug therapies. Robust mouse models of many human cancers have been generated using sophisticated technologies for engineering germ-line mutations. As we enter into an age of t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1421367/ https://ncbi.nlm.nih.gov/pubmed/16585951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28271 |
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