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Harnessing preclinical mouse models to inform human clinical cancer trials

The urgent need for better cancer treatments has stimulated interest in employing small-animal models to evaluate potential drug therapies. Robust mouse models of many human cancers have been generated using sophisticated technologies for engineering germ-line mutations. As we enter into an age of t...

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Autors principals: Gutmann, David H., Hunter-Schaedle, Kim, Shannon, Kevin M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421367/
https://ncbi.nlm.nih.gov/pubmed/16585951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28271
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