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Recognition of RNA by the p53 tumor suppressor protein in the yeast three-hybrid system

The p53 tumor suppressor protein is a homotetrameric transcription factor whose gene is mutated in nearly half of all human cancers. In an unrelated screen of RNA/protein interactions using the yeast three-hybrid system, we inadvertently detected p53 interactions with several different RNAs. A liter...

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Detalhes bibliográficos
Main Authors: RILEY, KASANDRA J.-L., CASSIDAY, LAURA A., KUMAR, AKASH, MAHER, L. JAMES
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2006 by RNA Society 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421098/
https://ncbi.nlm.nih.gov/pubmed/16581806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2286706
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