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Injury Induces Deficient Interleukin-12 Production, But Interleukin-12 Therapy After Injury Restores Resistance to Infection

OBJECTIVE: To assess at serial intervals the production of interleukin-12 (IL-12) by monocytes/macrophages from the peripheral blood of injured patients and control subjects, and using a mouse model to confirm human findings and explore the effectiveness of low-dose IL-12 therapy in restoring resist...

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Bibliographische Detailangaben
Hauptverfasser: Göebel, Andreas, Kavanagh, Eamon, Lyons, Ann, Saporoschetz, Inna B., Soberg, Christopher, Lederer, James A., Mannick, John A., Rodrick, Mary L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1420994/
https://ncbi.nlm.nih.gov/pubmed/10674618
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