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Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection.

OBJECTIVE: Patients with serious traumatic injury and major burns and an animal model of burn injury were studied to determine the effect of injury on the production of cytokines typical of the T helper-2 lymphocyte phenotype as opposed to the T helper-1 phenotype and on the production of interleuki...

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Main Authors: O'Sullivan, S T, Lederer, J A, Horgan, A F, Chin, D H, Mannick, J A, Rodrick, M L
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234878/
https://ncbi.nlm.nih.gov/pubmed/7574928
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