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Pulmonary surfactant inhibits monocyte bactericidal functions by altering activation of protein kinase A and C.

Pulmonary surfactant, the main function of which is to reduce surface tension in the alveoli, is also known to affect the functions of monocytes. Two protein kinases play a role in the regulation of the bactericidal functions of phagocytes, i.e. cAMP-dependent protein kinase A (PKA), which is involv...

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Dettagli Bibliografici
Autori principali: Geertsma, M F, Zomerdijk, T P, Nibbering, P H, van Furth, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415017/
https://ncbi.nlm.nih.gov/pubmed/7821958
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