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Anti-class II MHC antibodies prevent and treat EAE without APC depletion.

We have demonstrated that a murine IgG1 anti-class II major histocompatibility complex (MHC) antibody (OX6) is able both to prevent and treat experimental autoimmune encephalomyelitis (EAE) in the Biozzi AB/H mouse. We have confirmed that this antibody is poorly cytotoxic, allowing mechanisms of act...

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Sonraí Bibleagrafaíochta
Main Authors: Smith, R M, Morgan, A, Wraith, D C
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1994
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415013/
https://ncbi.nlm.nih.gov/pubmed/7821954
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