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Reactive Oxygen Species Inactivation of Surfactant Involves Structural and Functional Alterations to Surfactant Proteins SP-B and SP-C

Exposing bovine lipid extract surfactant (BLES), a clinical surfactant, to reactive oxygen species arising from hypochlorous acid or the Fenton reaction resulted in an increase in lipid (conjugated dienes, lipid aldehydes) and protein (carbonyls) oxidation products and a reduction in surface activit...

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Hlavní autoři: Rodríguez-Capote, Karina, Manzanares, Dahis, Haines, Thomas, Possmayer, Fred
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414557/
https://ncbi.nlm.nih.gov/pubmed/16443649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073106
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