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Size, Motion, and Function of the SecY Translocon Revealed by Molecular Dynamics Simulations with Virtual Probes

We report a hybrid, coarse-grained and atomistic, molecular dynamics simulation study of the size, motion, and function of the SecY protein-conducting channel. Growing and pushing virtual soft ball constructs through the pore of SecY, we mimic the push-through of polypeptides, performed cotranslatio...

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Bibliografske podrobnosti
Main Authors: Tian, Pu, Andricioaei, Ioan
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414555/
https://ncbi.nlm.nih.gov/pubmed/16461399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073304
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