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Synergistic roles of platelet-derived growth factor-BB and interleukin-1β in phenotypic modulation of human aortic smooth muscle cells

The phenotype of smooth muscle cells (SMCs) plays an important role in vascular function in health and disease. We investigated the mechanism of modulation of SMC phenotype (from contractile to synthetic) induced by the synergistic action of a growth factor (platelet-derived growth factor, PDGF-BB)...

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Detalhes bibliográficos
Main Authors: Chen, Cheng-Nan, Li, Yi-Shuan J., Yeh, Yi-Ting, Lee, Pei-Ling, Usami, Shunichi, Chien, Shu, Chiu, Jeng-Jiann
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413813/
https://ncbi.nlm.nih.gov/pubmed/16477012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510973103
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