Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells

We show that actin filaments, shortened to physiological lengths by gelsolin and cross-linked with recombinant human filamins (FLNs), exhibit dynamic elastic properties similar to those reported for live cells. To achieve elasticity values of comparable magnitude to those of cells, the in vitro netw...

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Bibliographic Details
Main Authors: Gardel, M. L., Nakamura, F., Hartwig, J. H., Crocker, J. C., Stossel, T. P., Weitz, D. A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413620/
https://ncbi.nlm.nih.gov/pubmed/16446458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504777103
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