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Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells

We show that actin filaments, shortened to physiological lengths by gelsolin and cross-linked with recombinant human filamins (FLNs), exhibit dynamic elastic properties similar to those reported for live cells. To achieve elasticity values of comparable magnitude to those of cells, the in vitro netw...

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Bibliografiske detaljer
Main Authors: Gardel, M. L., Nakamura, F., Hartwig, J. H., Crocker, J. C., Stossel, T. P., Weitz, D. A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413620/
https://ncbi.nlm.nih.gov/pubmed/16446458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504777103
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