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A detailed Hapmap of the Sitosterolemia locus spanning 69 kb; differences between Caucasians and African-Americans

BACKGROUND: Sitosterolemia is an autosomal recessive disorder that maps to the sitosterolemia locus, STSL, on human chromosome 2p21. Two genes, ABCG5 and ABCG8, comprise the STSL and mutations in either cause sitosterolemia. ABCG5 and ABCG8 are thought to have evolved by gene duplication event and a...

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Detalhes bibliográficos
Main Authors: Pandit, Bhaswati, Ahn, Gwang-Sook, Hazard, Starr E, Gordon, Derek, Patel, Shailendra B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413519/
https://ncbi.nlm.nih.gov/pubmed/16507104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-7-13
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