Two Adjacent Trimeric Fas Ligands Are Required for Fas Signaling and Formation of a Death-Inducing Signaling Complex

The membrane-bound form of Fas ligand (FasL) signals apoptosis in target cells through engagement of the death receptor Fas, whereas the proteolytically processed, soluble form of FasL does not induce cell death. However, soluble FasL can be rendered active upon cross-linking. Since the minimal exte...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Holler, Nils, Tardivel, Aubry, Kovacsovics-Bankowski, Magdalena, Hertig, Sylvie, Gaide, Olivier, Martinon, Fabio, Tinel, Antoine, Deperthes, David, Calderara, Silvio, Schulthess, Therese, Engel, Jürgen, Schneider, Pascal, Tschopp, Jürg
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2003
Θέματα:
Cell Growth and Development
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC141146/
https://ncbi.nlm.nih.gov/pubmed/12556501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1428-1440.2003
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