Two Adjacent Trimeric Fas Ligands Are Required for Fas Signaling and Formation of a Death-Inducing Signaling Complex

The membrane-bound form of Fas ligand (FasL) signals apoptosis in target cells through engagement of the death receptor Fas, whereas the proteolytically processed, soluble form of FasL does not induce cell death. However, soluble FasL can be rendered active upon cross-linking. Since the minimal exte...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Holler, Nils, Tardivel, Aubry, Kovacsovics-Bankowski, Magdalena, Hertig, Sylvie, Gaide, Olivier, Martinon, Fabio, Tinel, Antoine, Deperthes, David, Calderara, Silvio, Schulthess, Therese, Engel, Jürgen, Schneider, Pascal, Tschopp, Jürg
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141146/
https://ncbi.nlm.nih.gov/pubmed/12556501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1428-1440.2003
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker