Rho Family GTPases Are Required for Activation of Jak/STAT Signaling by G Protein-Coupled Receptors

As do cytokine receptors and receptor tyrosine kinases, G protein-coupled receptors (GPCRs) signal to Janus kinases (Jaks) and signal transducers and activators of transcription (STATs). However, the early biochemical events linking GPCRs to this signaling pathway have been unclear. Here we show tha...

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Detalhes bibliográficos
Main Authors: Pelletier, Stéphane, Duhamel, François, Coulombe, Philippe, Popoff, Michel R., Meloche, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141129/
https://ncbi.nlm.nih.gov/pubmed/12556491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1316-1333.2003
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