Adeno-Associated Virus Type 2-Mediated Gene Transfer: Role of Cellular T-Cell Protein Tyrosine Phosphatase in Transgene Expression in Established Cell Lines In Vitro and Transgenic Mice In Vivo

The use of adeno-associated virus type 2 (AAV) vectors has gained attention as a potentially useful alternative to the more commonly used retrovirus and adenovirus vectors for human gene therapy. However, the transduction efficiency of AAV vectors varies greatly in different cells and tissues in vit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qing, Keyun, Li, Weiming, Zhong, Li, Tan, Mengqun, Hansen, Jonathan, Weigel-Kelley, Kirsten A., Chen, Linyuan, Yoder, Mervin C., Srivastava, Arun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Gene Therapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141114/
https://ncbi.nlm.nih.gov/pubmed/12552015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2741-2746.2003
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