G Protein-Dependent CCR5 Signaling Is Not Required for Efficient Infection of Primary T Lymphocytes and Macrophages by R5 Human Immunodeficiency Virus Type 1 Isolates
The requirement of human immunodeficiency virus (HIV)-induced CCR5 activation for infection by R5 HIV type 1 (HIV-1) strains remains controversial. Ectopic CCR5 expression in CD4(+)-transformed cells or pharmacological inhibition of G(α)i proteins coupled to CCR5 left unsolved whether CCR5-dependent...
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| Опубліковано в:: | J Virol |
|---|---|
| Автори: | , , , , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Microbiology (ASM)
2003
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141084/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12551993/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.4.2550-2558.2003 |
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