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Murine Gammaherpesvirus 68 Lacking Thymidine Kinase Shows Severe Attenuation of Lytic Cycle Replication In Vivo but Still Establishes Latency

The lytic cycle functions of gammaherpesviruses have received relatively little attention to date, at least in part due to the lack of a convenient experimental model. The murine gammaherpesvirus 68 (MHV-68) now provides such a model and allows the roles of individual lytic cycle gammaherpesvirus pr...

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Udgivet i:J Virol
Principais autores: Coleman, Heather M., Lima, Brigitte de, Morton, Victoria, Stevenson, Philip G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141081/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12551978/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.4.2410-2417.2003
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