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Murine Gammaherpesvirus 68 Lacking Thymidine Kinase Shows Severe Attenuation of Lytic Cycle Replication In Vivo but Still Establishes Latency

The lytic cycle functions of gammaherpesviruses have received relatively little attention to date, at least in part due to the lack of a convenient experimental model. The murine gammaherpesvirus 68 (MHV-68) now provides such a model and allows the roles of individual lytic cycle gammaherpesvirus pr...

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Bibliographische Detailangaben
Hauptverfasser: Coleman, Heather M., Lima, Brigitte de, Morton, Victoria, Stevenson, Philip G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141081/
https://ncbi.nlm.nih.gov/pubmed/12551978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2410-2417.2003
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