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Murine Gammaherpesvirus 68 Lacking Thymidine Kinase Shows Severe Attenuation of Lytic Cycle Replication In Vivo but Still Establishes Latency

The lytic cycle functions of gammaherpesviruses have received relatively little attention to date, at least in part due to the lack of a convenient experimental model. The murine gammaherpesvirus 68 (MHV-68) now provides such a model and allows the roles of individual lytic cycle gammaherpesvirus pr...

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Autors principals: Coleman, Heather M., Lima, Brigitte de, Morton, Victoria, Stevenson, Philip G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC141081/
https://ncbi.nlm.nih.gov/pubmed/12551978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2410-2417.2003
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